Cilcare

Science and sport share a common drive: pushing boundaries. At Cilcare, we embrace this spirit every day. Like athletes refining their skills, we strive for excellence in hearing research, constantly innovating and overcoming challenges. Both fields are about progress, perseverance, and reaching new heights. Celebrating together the start of the Paris Olympics!

🎧🌟 Santé Auditive et Intelligence Artificielle : comment vivre en bonne santé ? 🌟🎧 C’est dans cette Tribune de Bpifrance que Celia Belline, CEO de Cilcare, met en lumière l'impact révolutionnaire de l'intelligence artificielle sur la santé auditive. La technologie et l'innovation transforment notre approche des soins auditifs, offrant des solutions de plus en plus personnalisées et efficaces. Grâce à l'IA, nous travaillons à améliorer la détection, le diagnostic et le traitement des problèmes auditifs et des maladies chroniques associées avec une précision sans précédent. 🔍 Découvrez la tribune: https://lnkd.in/dBNxe5-P Chez Cilcare, nous sommes à l'avant-garde des avancées dans le secteur de la santé auditive. En tant que membre excellence de Bpifrance, notre engagement à innover et à repousser les limites de ce qui est possible nous permet de développer des solutions de pointe pour améliorer la santé auditive et globale à l'échelle mondiale. 🎯 #SantéAuditive #IntelligenceArtificielle #Innovation #Technologie #BienÊtre #Bpifrance #Audiologie #bigmedia

🚀 Offre d'Alternance chez Cilcare ! 🚀 Vous êtes passionné(e) par le développement web et l'audition vous intéresse ? Rejoignez-nous pour développer notre nouvelle plateforme web clinique ! Vos missions : 🔹 Développer une interface web full-stack ergonomique 🔹 Sécuriser l'accès et participer à l'industrialisation du déploiement Qualifications : 🔹 Maîtrise de React en Frontend et Python en Backend 🔹 Expérience avec GCP (Google Cloud Platform) est un + 🔹 Intérêt pour la santé et la recherche clinique Accéder à l’offre ici https://lnkd.in/e4FvtHD7 et envoyez votre candidature à careers@cilcare.com. #Recrutement #Alternance #DéveloppementWeb #Santé #Cilcare

🚀 Join us to drive breakthroughs for hearing health ! 🚀 Cilcare is looking for a passionate Project Manager in Drug Development to join our innovative team. We are at the forefront of auditory science, specializing in the preclinical and clinical evaluation of novel therapies to address different forms of ear disorders. We are driven by a mission to transform lives through groundbreaking solutions for hearing health. 👉 Your role: 🔹 Develop and execute project plans 🔹 Coordinate resources and timelines 🔹 Facilitate cross-functional collaboration 🔹 Ensure quality and regulatory compliance 👉 Why Join Us? 🔹 Flexibility: Embrace a flexible remote and on-site work arrangement 🔹 Innovation: Be part of a pioneering company recognized globally 🔹 Impact: Contribute to life-changing therapies for hearing loss and associated diseases 👉 Qualifications: 🔹 MS, PhD, or PharmD with 3+ years in clinical development 🔹 Strong leadership and project management skills 🔹 Fluent in English Ready to make a difference? See the job offer here: https://lnkd.in/eVrxWsjn and apply directly at careers@cilcare.com #JobOpportunity #ProjectManager #DrugDevelopment #Biotech #HearingScience #JoinOurTeam #InnovativeMedicine #FlexibleWork #HiringNow  

🌟 Inner Ear Organoids: Exciting in vitro model development showcased at the global Stem Cell Event last week in Hambourg 🌟 Last week at ISSCR, Sylvie Pucheu, Léa Jaillot, Ezeddine Harmouch and Azel Z. from LBN Montpellier University presented their recent work on an Efficient Embryoid-based Method to Improve Generation of Otic Vesicles from Human Induced Pluripotent Stem Cells. This 3D in vitro strategy aims to better understand the mechanisms of human otic development and test novel regenerative therapies to combat hearing loss and balance impairments. 🔬 Innovation: The research team adapted a protocol to improve embryoid body-based otic induction from hiPSCs, preserving the integrity and viability of cells forming the otic embryoid bodies (OEBs) and otic vesicle-like structures. Using a Sox2-GFP reporter hiPSC line, we tracked the progression from pluripotency to otic progenitors, showing robust otic induction and improved vesicle generation between days 11-60 of cell cultures. This is a great milestone for the OrgaEar project directed by Professor Azel Zine, that we conduct in collaboration with the University of Montpellier and the support of SATT AxLR. #Organoids #Innovation #StemCells #InVitroModels #TherapiesDevelopment #InnerEarPathologies #ISSCR2024 #HearingResearch #RegenerativeMedicine

Hello Summer! 🌞 Our team at Cilcare just enjoyed a fantastic oyster park outing near Montpellier—boat tour and all, followed by a seafood feast! It's moments like these that bring us closer together and remind us why we love what we do. Here's to many more sunny adventures together! 🚤🦪 #TeamOuting #SummerVibes #LifeAtCilcare

🔬 Cilcare leading the way in cutting-edge cochlear explant research! 🧬 At Cilcare, we are at the forefront of auditory research, utilizing advanced ex vivo models to assess ototoxicity and otoprotection. One of our key areas of expertise is cochlear explant technology. 🧪 Why Cochlear Explants? Cochlear explants provide a robust ex vivo model to evaluate the ototoxic effects and otoprotective properties of various compounds. This technique is instrumental in our efforts to understand and mitigate hearing loss, particularly in the context of ototoxicity induced by medications like cisplatin. 💡 Recent Findings: Our latest research has revealed significant disorganization of cochlear hair cells following cisplatin treatment, observable all along the cochlea tonotopy. We also observed significant decrease of inner and outer hair cell density in the cisplatin group. This disruption highlights the ototoxic impact of cisplatin and underscores the importance of developing protective strategies. 💡 Key Benefits: 🔹 Accurate Assessment of Ototoxicity: We use cochlear explants to precisely evaluate how different compounds affect the cochlea, enabling us to identify potential ototoxic agents early in the drug development process. 🔹Otoprotection Research: Our team also investigates protective strategies against ototoxicity, focusing on cisplatin-induced hearing loss. This research is crucial for developing therapies that can safeguard patients' hearing during essential treatments. Our commitment to advancing auditory science is driven by our passion for improving the quality of life for those affected by hearing loss. By leveraging cutting-edge models like cochlear explants, we strive to lead the way in discovering innovative solutions for otoprotection and hearing preservation. 📞 Interested in learning more about our services or collaborating with us? Have a look here https://lnkd.in/eth85Q8D and reach out today to explore how we can support your research and development needs. #AuditoryResearch #CochlearExplant #Ototoxicity #Otoprotection #Cisplatin #HearingLoss #InnovativeResearch #LifeSciences #HearTheFuture

🔬 Cilcare attending the ISSCR 2024 in Hamburg this week ! 🌍 Join Sylvie Pucheu, Director of preclinical Innovation & co-founder at the prestigious International Society for Stem Cell Research (ISSCR) Congress in Hamburg ! Highlight: 👉 Poster Presentation by Azel Zine: We are proud to highlight a poster presentation by Azel Z., Professor at Montpellier University, co-written with Cilcare, showcasing our latest advancements in in vitro auditory research. The poster, titled "Efficient Embryoid-Based Method to Improve Generation of Otic Vesicles from Human Induced Pluripotent Stem Cells," presents an innovative approach to creating in vitro models of the human inner ear using human induced pluripotent stem cells (hiPSCs). This method enhances the generation of otic vesicles, providing a robust platform for cell therapy and drug testing. 👉 OrgaEar Project Spotlight: Cilcare, in collaboration with the University of Montpellier and with the support of SATT AxLR, is developing an organoid model of the inner ear. Initiated in May 2023, OrgaEar aims to generate cochlear organoids containing neurosensory cells from the human inner ear using human induced pluripotent stem cell technology and 3D cell culture. This innovative preclinical model will allow the testing of drug candidates aimed at protecting or regenerating inner ear cells, offering a vital tool for auditory research and eliminating the need for in vivo experiments. Join us in celebrating this milestone and our commitment to advancing auditory science through innovative stem cell research. We look forward to connecting with fellow researchers and industry leaders at ISSCR 2024! #ISSCR2024 #StemCellResearch #AuditoryScience #MontpellierUniversity #AxLR #InnovativeResearch #HearingHealth

Lancement de la saison estivale avec la très dynamique émission « 100% HealthTech, le décryptage » de France Biotech et la question : est-ce que 2024 s'annoncerait comme la grande année des partenariats pour la #biotech ?  J’ai eu l’immense plaisir de débattre sur ce sujet, illustré par notre récent partenariat avec Shionogi & Co., Ltd, aux côtés de Fabrice Lundy, Sonia de Kondserovsky d'DLA Piper, et Eric COHEN d'Agile Capital Market. Merci à France Biotech, pour cette opportunité d’expliquer plus en avant notre stratégie et les prochaines étapes de notre développement.    Pour le Replay, voir en commentaire plus bas▾ #100HealthTech #FranceBiotech #HealthTech #Innovation #Cilcare #Paris #Ophtalmologie #BiotechFinances

📣 Cilcare remporte le Grand Prix du Meilleur Poster aux AFSSI Connexions ! 🏆 Intitulé "Sensorineural hearing loss as a complication of type-2 Diabetes mellitus: evidence of several cellular and neural impairments" et présenté par Sylvie Pucheu, notre poster a montré que la perte auditive neurosensorielle est une complication du diabète de type 2, résultant de plusieurs altérations cellulaires et neuronales. En utilisant un modèle préclinique, nous avons démontré que le diabète entraîne une perte auditive précoce et des changements morphologiques dans la cochlée. Ce modèle pourrait servir à évaluer de nouveaux traitements pour préserver et restaurer l'audition chez les patients diabétiques. Merci à l'AFSSI Sciences de la Vie et au jury pour cette reconnaissance ! Félicitations à ATLANTIC BONE SCREEN et ENTEROSYS - Gut Is The Link qui ont reçu le prix du public !🚀 #AFSSI2024 #Recherche #Diabète #Innovation #SantéAuditive