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View profile for Jean-Christophe Chiêm, PhD, graphic

Turning Data into Patients' Value

I will be honoured to talk at the ICTM webinar this Monday 8th july organized by Institute of Clinical Trials and Methodology at UCL and MRC Clinical Trials Unit at UCL   I will address issues of non-inferiority #NItrials which are often impractical and pose several challenges compared to superiority trials. Our statistical method of generalized pairwise comparison (#GPC) can tackle some of these issues by allowing the simultaneous evaluation of #multipleoutcomes of interest, adopting an adequate #prioritization according to their perceived clinical importance. This solution has led us to drastic #samplesize #reduction and a formulation of the research questions promoting #patientcentricity, as detailed in this case study.

Design of a clinical trial using generalized pairwise comparisons to test a less intensive treatment regimen - PubMed

Design of a clinical trial using generalized pairwise comparisons to test a less intensive treatment regimen - PubMed

pubmed.ncbi.nlm.nih.gov

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