The Emerging Role of the Sympathetic Nervous System in Skeletal Muscle Motor Innerfvation and Sarcopenia

Osvaldo Delbono; Anna Carolina Zaia Rodrigues; Henry Jacob Bonilla; Maria Laura Messi

doi:10.1016/j.arr.2021.101305

Figure 2.

An external file that holds a picture, illustration, etc.
Object name is nihms-1677965-f0002.jpg

Downregulation of preterminal adrenergic receptors and its impact on motoneuron synaptic vesicle release with aging.

AP: axon potential. Red arrows indicate decreased function or protein expression with aging. Dashed lines indicate proposed pathways. Adapted from (Rodrigues et al., 2019; Wang et al., 2020a). AP: action potential; EPP: end-plate potential; NA: noradrenaline; QC: quantal content; tSC: terminal Schwann cell; VGCC: voltage-gated calcium channel.